Abstract
Spirogram, transpulmonary pressure, intraesophageal, intrapleural pressure, and pressure in a closed bronchus were recorded in 16 healthy rabbits under thiopental anesthesia (first series). Dead rabbits were placed in a chamber, where respiratory movements were simulated by changing pressure, and all the parameters were recorded (second series). The lungs were then isolated and placed in the Donders bell (third series). Deformation of the plateau in transpulmonary pressure during a 0.5-sec interruption of air flow was observed only in the first series of experiments. The amplitude of pressure in a closed bronchus exceeded intrapleural pressure only in the first series. It is concluded that pleura does not contribute to the paradoxical mechanics of respiration.
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