Abstract
MCL-1 is an anti-apoptotic protein that regulates cell apoptosis and has been observed in over-expression in manycancer. It makes the MCL-1 an available target. S63845 is introduced to treat cancer, an inhibitor with a high affinity toMCL-1. However, the tolerability of the human body to the treatment remains unanswered. Therefore in this paper, wedesigned the experiment to test the tolerability of regular issue glandular with cancerous individuals of the same cellline, the apoptosis will be tested by the MTT theory, and the direct production of inhibition --BAX will be measuredby western blot. The result is predicted, and this work will provide meaningful information for future cancer treatment.Future studies should focus on cooperation with other BCL-2 inhibitors and the impact of the treatment.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
