Abstract
Recent studies in murine and human endometrium have suggested the possibility of a steroidogenic capacity, but details of steroid biosynthetic enzyme expression and their potential regulation by cyclic hormones and/or endometriosis remain unclear. The objective of this study was to characterize the cycle and disease regulation of eutopic endometrial mRNA coding for the 3 essential components of progesterone (P) biosynthesis: steroid acute regulatory protein (StAR, mediates cholesterol transport), Cholesterol 20-22 Desmolase (CYP11A1, catalyzes cleavage of the cholesterol side chain to form pregnenolone), and 3-Beta-HSD, type I (HSD3B1, catalyzes conversion of pregnenolone to progesterone).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
