Abstract
BackgroundFracture of the proximal femur is the most feared complication of osteoporosis. Given the numerous physiological functions that magnesium performs in our body, in the literature there is a correlation between osteoporosis and low serum levels of magnesium.AimEvaluate the incidence of hypomagnesemia in patients with lateral fragility fracture of the proximal femur, the possible correlation between serum magnesium levels and fractures, and the effectiveness of supplementing Sucrosomial® magnesium associated with therapeutic exercise on the outcome of these patients.MethodsWe divided the study into two parts. In the first part, we assessed the preoperative incidence of hypomagnesemia in patients using a blood test. In the second part, patients with hypomagnesemia were divided, in the post-operative period, into two groups, who received, respectively, only therapeutic exercise or oral supplementation with sucrosomial magnesium associated with therapeutic exercise.ResultsHalf of the patients with fragility femoral fracture had hypomagnesemia, with a higher incidence of the subclinical form. From the comparison between the two groups, the T1 treatment group showed a significant improvement in blood levels of magnesium (2.11 ± 0.15 vs. 1.94 ± 0.11; p < 0.05), on the NRS scale (5.7 ± 0.81 vs. 6.6 ± 1.18; p < 0.05), the Tinetti scale (17.3 ± 1.15 vs. 15.2 ± 2.98; p < 0.05) and the SarQoL questionnaire (47.3 ± 5.21 vs. 44.9 ± 5.54; p < 0.05).ConclusionsMore attention would be needed in the diagnosis and correction of subclinical hypomagnesemia and not just the simple and clinically evident one, including hypomagnesemia among the modifiable risk factors for osteoporosis.
Highlights
The fracture of the proximal portion of the femur is the most feared complication of osteoporosis.Along with vertebral fractures, they are defined as brittle fractures, as they can occur as a result of low-energy trauma as a result of reduced bone mass and changes in bone structure [1].This type of fracture accounts for 83% of hospitalization causes in osteoporotic patients
Special attention should be paid to modifiable risk factors (cigarette smoking, alcohol, reduced body mass index (BMI), physical inactivity, and nutritional deficiencies)
Their deficiency can have negative effects on the health of the bone, in the literature a correlation is known between osteoporosis and low serum levels of magnesium and/ or vitamin
Summary
They are defined as brittle fractures, as they can occur as a result of low-energy trauma as a result of reduced bone mass and changes in bone structure [1] This type of fracture accounts for 83% of hospitalization causes in osteoporotic patients. An important role in bone metabolism is played by some electrolytes, such as magnesium, and vitamins, like vitamin K Their deficiency can have negative effects on the health of the bone, in the literature a correlation is known between osteoporosis and low serum levels of magnesium and/ or vitamin. Aim Evaluate the incidence of hypomagnesemia in patients with lateral fragility fracture of the proximal femur, the possible correlation between serum magnesium levels and fractures, and the effectiveness of supplementing S ucrosomial® magnesium associated with therapeutic exercise on the outcome of these patients. Conclusions More attention would be needed in the diagnosis and correction of subclinical hypomagnesemia and not just the simple and clinically evident one, including hypomagnesemia among the modifiable risk factors for osteoporosis
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