Abstract
Background:Breast cancer is the most prevalent cancer in women worldwide. Treatment for breast cancer can be expensive, painful and can significantly affect the quality of life, leading to various side effects such as depression and anxiety, fatigue, sleep disorders, and cognitive impairment. Tai Chi Chuan (TCC) is the most prominent manifestation of tai chi in Chinese martial arts. TCC has been reported to be potentially effective for health and well-being of both the sick and the healthy. However, it is still controversial whether TCC benefits breast cancer patients. It is therefore of great value to evaluate the effectiveness of TCC on the psychological well-being and quality of life in people with breast cancer.Methods:This review will summarize and meta-analyze all relevant randomized controlled trials on TCC in patients with breast cancer in the light of their anxiety, depression and fatigue level, inflammatory cytokine as well as quality of life, sleep quality, and cognitive function. The following electronic databases will be searched: PubMed, Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure Database, Chinese Biomedical Literature Database, VIP Chinese Science and Technology Periodical Database, and Wan Fang Data. The methodologic quality of randomized controlled trials has been assessed using the Cochrane risk assessment tool. All trials included are analyzed according to the criteria of the Cochrane Handbook. Review Manager 5.3, R-3.5.1 software and grading of recommendations assessment, development, and evaluation pro-GDT online software are used for data synthesis and analysis.Results:The results of this systematic review will be used to summarize and evaluate the evidence available from randomized controlled clinical trials of TCC as supportive and adjuvant therapy for breast cancer.Conclusion:This review will provide a detailed summary of the evidence to assess the effectiveness of TCC for breast cancer.OSF Registration:DOI 10.17605/OSF.IO/Z2FSA.
Highlights
Breast cancer is the most common cancer diagnosed globally in women and accounts for about 25% of all types of cancer in women.[1,2] The incidence of breast cancer is rising and the rate of mortality falling in developing countries with about 70% of deaths occurring.[3]
An increasing number of clinical studies have indicated the safety and health benefits of Tai Chi Chuan (TCC) intervention for breast cancer patients. It is still controversial whether TCC benefits breast cancer patients on the quality of life, physical and psychological health and other important clinical endpoints
Studies have shown that nearly half the cancer patients develop depressive symptoms during treatment, and the rate is high among breast cancer patients, at least twice as high as those without breast cancer.[31,32]
Summary
Breast cancer is the most common cancer diagnosed globally in women and accounts for about 25% of all types of cancer in women.[1,2] The incidence of breast cancer is rising and the rate of mortality falling in developing countries with about 70% of deaths occurring.[3]. Breast cancer survivors often use complementary therapies as supportive care during cancer treatment, with the aim of strengthening health, improving quality of life, and alleviating disease symptoms and side-effects associated with conventional treatments. Treatment for breast cancer can be expensive, painful and can significantly affect the quality of life, leading to various side effects such as depression and anxiety, fatigue, sleep disorders, and cognitive impairment. TCC has been reported to be potentially effective for health and well-being of both the sick and the healthy. It is still controversial whether TCC benefits breast cancer patients. It is of great value to evaluate the effectiveness of TCC on the psychological well-being and quality of life in people with breast cancer
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
