Abstract
BackgroundPatients with systemic lupus erythematosus are more likely to receive THA than the general population. However, it is controversial whether SLE increases the risk of complications from THA. The purpose of this retrospective study was to reassess the risks from THA in patients with SLE under the management model of enhanced recovery after surgery.MethodsPatients with systemic lupus erythematosus diagnosed from December 2011 to December 2017 and treated with THA were compared with THA patients with osteoarthritis. The data were extracted from the medical record system of our department. The chi-square test and t-test were used for comparison.ResultsThe postoperative blood loss in patients with SLE was significantly higher than that in the control group, and the postoperative hemoglobin (Hb) and hematocrit (Hct) in the control group were lower than those in the control group (P < 0.05). There was no significant difference in the rate of blood transfusion (9.733 vs 8.133 P = 0.3148) or other complications between the two groups (P > 0.05).ConclusionWell-controlled and well-managed SLE will not increase the risk of complications in THA, but can increase the amount of perioperative blood loss. Therefore, perioperative blood management is still essential in SLE patients.
Highlights
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect a variety of systems including bones and joints [1]
Clinical data The indicators included the patient’s baseline demographic characteristics, American Society of Anesthesiologists rating, coexisting diseases, preoperative Harris Hip Score (HHS) score, preoperative hematological indicators (hemoglobin(Hb), albumin(Ab), platelets(Plt), hematocrit(Hct), Erythrocyte sedimentation rate (ESR), Creactive protein(CRP)), intraoperative dominant bleeding, postoperative hematological indicators (Hb, Ab, Plt, Hct), perioperative adverse events, total blood loss, length of stay (LOS), HHS score and 12-item Short-Form Health Survey (SF-12) score at the last follow-up
Compared with the control group, there was no significant difference in the incidence of blood transfusion in the SLE group
Summary
Patients with systemic lupus erythematosus diagnosed from December 2011 to December 2017 and treated with THA were compared with THA patients with osteoarthritis. The data were extracted from the medical record system of our department. The chi-square test and t-test were used for comparison
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