Does SIRS need to be abandoned

Abstract

Recently, the Society of Critical Care Medicine and the European Society of Intensive Care Medicine sponsored a 19-member Task Force to update the definitions of sepsis and septic shock at the forty-fifth Critical Care Medicine Annual Meeting in February 2016.Owing to an increased understanding of the harmful systemic response to infection, members of the multidisciplinary task force proposed that sepsis now be defined as life threatening organ dysfunction caused by a dysregulated host response to infection . To standardize the assessment of organ dysfunction, the Task Force members propose that provider use the sequential organ failure assessment(SOFA) score and quick SOFA (qSOFA). Although the systemic inflammatory response syndrome(SIRS) standard has high sensitivity and low specificity, the mortality of sepsis in the world has decreased significantly in the past 20 years.With the gradual realization of sepsis 3.0, will SIRS really be completely out of the stage of history? The SOFA and qSOFA criteria is not suitable for children.The author thinks that SIRS standard still has its practical application value.We need further studies on how to improve the sensitivity and specificity of sepsis diagnosis at the same.We should continue to validate sepsis 3.0. Key words: Sepsis; Organ dysfunction; Systemic inflammatory response syndrome,