Abstract
In relapsing–remitting multiple sclerosis (RRMS), is relapse occurrence or frequency predictive of either major disability (sustained need for aid in walking) or entry into the secondary progressive (SPMS) phase? To find out, researchers retrospectively examined data on almost 2500 patients from their unique (in the Western Hemisphere) population-based British Columbia Multiple Sclerosis database. The primary outcomes were time to Expanded Disability Status Scale (EDSS) score of 6.0 and time to SPMS. The authors first assessed outcomes with Kaplan-Meier “survival” curves for three levels of frequency of bouts occurring only within the first 5 years after MS onset. They then used Cox proportional hazard ratios (HRs), adjusted for sex, age at onset, and nature of …
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
