Abstract
Considerable research has been carried out over the last 30 years to investigate whether regional anaesthesia improves the quality of postoperative analgesia compared with systemic opioids, and whether it influences the outcome from surgery. Some benefits, such as the quality of postoperative analgesia, are easy to demonstrate but the intuitive belief that regional anaesthesia improves the outcome from surgery is more difficult to prove. Many studies have been inconclusive, with methodological weaknesses making it difficult to compare the results of different studies. Nevertheless, the weight of evidence suggests that regional anaesthesia has the potential to improve outcome from surgery.
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