Does preoperative inferior endplate morphology influence the outcomes of cervical disc arthroplasty at C5-C6 level: A retrospective study

Abstract

ObjectivesDespite encouraging clinical results, the postoperative segmental kyphosis was observed in many cervical disc arthroplasty (CDA) studies. Most studies discussed technical factors related to kyphosis. However, the cervical endplate, which contacted directly with prostheses and distributed the compressive load across the vertebral body, was seldom investigated. The purpose of the study was to investigate the effects of the inferior endplate morphology on clinical and radiological outcomes after C5/C6-level CDA with Prestige-LP Disc. Patients and methodsOne hundred and thirty-two patients with C5/C6-level CDA were retrospectively reviewed. Their preoperative inferior endplates on the mid-sagittal plane were visually classified into 3 types: type I with the endplate concavity apex located posteriorly, type II with the apex located in the middle and type III with the apex located anteriorly. Sagittal diameter of endplate, endplate concavity depth and endplate concavity apex location were measured. Japanese Orthopedic Association (JOA), visual analogue scale (VAS) and Neck Disability Index (NDI) scores were used to evaluate clinical outcomes. Range of motion (ROM) and sagittal alignment including C2-7 and C5-6 angle were assessed. ResultsThe type I, type II and type III endplates accounted for 25.00 %, 51.52 % and 23.48 % of 132 individuals. Most patients achieved significant reduction in VAS scores and NDI but the significant increase in JOA scores. No substantial differences in clinical outcomes were found among the 3 endplate types. Compared with preoperative values, the C5-6 ROM, C2-7 ROM and C2-7 angle were preserved, while the C5-6 angle increased significantly from kyphosis to lordosis. At the last follow-up, type I endplate had the least C5-6 angle (2.03°, 3.94° and 4.46° for type I, II and III endplates) and the highest incidence of segmental kyphosis at C5-C6 level (33.30 %, 14.70 % and 9.70 % in the same order, P = 0.028). ConclusionsPatients achieved satisfactory clinical outcomes after C5/C6-level CDA without significant differences among three endplate types. Type I endplate had a high incidence of segmental kyphosis at C5-C6 level.