Abstract
The mechanisms regulating human oocyte maturation in vivo or in vitro are not well characterized. Previous studies employing inhibition of protein synthesis or targeted ablation of the endogenous Mos mRNA, have suggested a role for regulated Mos RNA translational control during human oocyte maturation. However, while a cytoplasmic polyadenylation element binding protein (CPEB1) has been characterized and shown to be expressed in human oocytes, it has not been determined if regulated cytoplasmic polyadenylation of the maternal Mos mRNA occurs during human oocyte maturation.
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