Abstract
Background. In this pilot observational study, we aimed to investigate the effect of preoperative magnesium infusion on laryngospasm frequency and other res-piratory complications in children with respiratory findings undergoing esopha-geal dilatation after the ingestion of caustic substances.Methods. Sixty children between the ages of 2 and 12 scheduled for esophageal dilatation were divided into two groups: the magnesium group (Group M), which consisted of children with respiratory symptoms and who received IV 30 mg/kg magnesium sulfate preoperatively, and the control group (Group C), who received the same volume of saline. Anesthesia was induced with fentanyl, propofol, and miva-curium and maintained using a 60% N2O and 2-3% sevoflurane mixture in oxygen. Demographic and hemodynamic data, as well as the incidence of respiratory com-plications (laryngospasm, bronchospasm, apnea, cough, and desaturation) during the perioperative period were recorded until the time of discharge from the recov-ery room.Results. Demographic data and hemody-namics were similar in the two groups. The laryngospasm, bronchospasm, apnea, and cough incidences were also similar between the groups, although the desatu-ration incidence was lower in Group M than in Group C (p=0.013). The number of complications in total was lower in Group M as well (p=0.008), although the number of children who experienced complica-tions in each group was similar.Conclusion. Prophylactic administration of 30 mg/kg of magnesium to children with respiratory symptoms may decrease the frequency of postoperative respiratory complications in children undergoing es-ophageal dilatation.
Highlights
Esophageal injury caused by caustic substances in children generally occurs after children accidentally drink cleaning agents
In this pilot observational study we aimed to investigate the effect of preoperative magnesium infusion on the frequency of laryngospasm and other respiratory complications in children with pathological auscultation findings undergoing esophageal dilatation after the ingestion of caustic substances
If bronchospasm was encountered in the perioperative period, the following treatment was planned: 100% O2 with manual bag ventilation, increased depth of anesthesia, and four to eight puffs of salbutamol with an metered-dose inhaler (MDI) (100 μg) spacer through an endotracheal tube at 20to 30-minute intervals
Summary
Esophageal injury caused by caustic substances in children generally occurs after children accidentally drink cleaning agents. When one considers that respiratory complications are more frequent in children with respiratory tract problems, magnesium may be beneficial. In this pilot observational study we aimed to investigate the effect of preoperative magnesium infusion on the frequency of laryngospasm and other respiratory complications in children with pathological auscultation findings undergoing esophageal dilatation after the ingestion of caustic substances. Prophylactic administration of 30 mg/kg of magnesium to children with respiratory symptoms may decrease the frequency of postoperative respiratory complications in children undergoing esophageal dilatation.
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