Abstract

PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) are characterized by sudden onset of obsessive-compulsive disorder (OCD) symptoms following streptococcal infections in prepubertal children. Similar to other post-streptococcal syndromes (e.g., Syndenham chorea), patients with PANDAS have antibodies that cross-react with basal ganglia. Thus, it was reasonable for investigators to …

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