Abstract
Ablative mandibular resection may result in neurosensory loss and decreased quality-of-life, yet nerve reconstruction is not performed routinely for various reasons, including increased operative time. This study aimed to determine whether immediate inferior alveolar nerve (IAN) allograft reconstruction provides functional sensory recovery (FSR) in the pediatric age group. This multicenter retrospective cohort study included pediatric patients who underwent mandibular resection with IAN discontinuity and a nerve allograft greater than 45mm. A positive control group also was included, comprising pediatric patients who underwent mandibular resection without nerve reconstruction. The primary predictor variable was the use of a nerve allograft; a secondary variable was the time to achieve FSR using the Medical Research Council Scale. Comparisons were made to historical adult data. Statistical analysis of the comparison of neurosensory outcomes over time was measured by weighted values, repeated-measures analysis of variance, and the McNemar test. The study group consisted of 32 patients, 18 in the graft group and 14 in the non-graft group, without significant differences in age, gender, or nerve gap length. By 1year, FSR was achieved in 100% in the study group and 0% in the control group (P<.00001). The median time to FSR was 75days in the study group and 110days in the historical adult study group. In comparison to historical adult data, there was a significant difference at 1year, with adults at 87% FSR (P=.01562). Long-span nerve allografts were effective in restoring sensation to the lip and chin in pediatric patients, with 100% reaching FSR, whereas no patients without nerve reconstruction achieved FSR. Pediatric patients recovered to a higher level of FSR than adults at 1year. Immediate IAN reconstruction in pediatric patients should be considered strongly when the mandible requires resection with sacrifice of the IAN.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
