Abstract
Objective: Homologous recombination deficiency (HRD), identified by HRD genomic alterations (GA) or percentage gLOH, correlates with PARP inhibitor response in ovarian cancer (OC). Since the copy number high (CN-H) TCGA EC molecular subtype (EC-MS) shares molecular features with high-grade OC, our aim was to evaluate the role of gLOH in predicting PS and as a marker of HRD.
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