Abstract

Objective: The aim of this study is to identify the impact of preoperative clinical symptoms of biliary colic –whether classic, dyspeptic or atypical type- on operative or non-operative clinical outcome. Study Design: Prospective study. Settings: Department of Surgery, Sargodha Medical College, Sargodha Pakistan. Duration: 15-01-2016 to 01-12-2017. Methods: Randomize control trial. Results:106 patients with cholelithiasis were evaluated, out of which 86.79% (n- 92) underwent cholecystectomy. 91.3% (n-84) were asymptomatic postoperatively. More than 50% patients presented with associated symptoms like GIRD/reflux, dyspepsia (n-57). Heartburn/reflux patients were unresolved postoperatively (P=0.03). Overall, 12.2% (n-13) of patients and 21.2% of patients with associated symptoms improve with medical treatment of peptic ulcer/H-pylori triple regimen therapy pre/postoperatively. Conclusion: Patients with symptomatic gall stone associated with atypical presentation, may benefit from PPI treatment or H. pylori testing before cholecystectomy.

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