Does Bariatric Surgery Affect Intraocular Pressure?

Abstract

The effect of body mass index (BMI) reduction following bariatric surgery on intraocular pressure (IOP) is not well established. We evaluated association between BMI reduction and IOP measurements and other ocular and metabolic parameters 1year after bariatric surgery. A retrospective study with over 1-year follow-up on patients who underwent weight reduction bariatric surgery between January 2016 and December 2016 at Wolfson Medical Center, Israel. Patient data was extracted from outpatient's bariatric and ocular clinic records. Metabolic, ocular, and clinical parameters were assessed including BMI changes, IOP, central corneal and retinal nerve fiber layer thickness, optical coherence tomography, and biometry results. Of 22 bariatric surgery patients, 15 underwent laparoscopic sleeve gastrectomy (LSG) and 7 laparoscopic mini gastric bypass (MGB). All were followed up for over 1year after surgery. Average BMI decreased from 41.9 ± 7.3 to 25.5 ± 5.7kg/m2 at 1-year follow-up (p < 0.001). Mean IOP decreased significantly by 21% after 1year (p < 0.001). Decrease in IOP 1year after surgery was correlated with decrease in IOP at 3-month follow-up (r = 0.677, p = 0.001), preoperative IOP (r = 0.837, p < 0.001), and corneal thickness (r = 0.589, p = 0.006), with no correlation between reduction in IOP and baseline weight, BMI, or the reduction in either (p > 0.05). Central corneal thickness and retinal nerve fiber layer thickness were also significantly decreased (p = 0.038) and (p = 0.018), respectively. BMI reduction achieved by bariatric surgery was associated with significant and continued decline in IOP beyond 1year after surgery. Clinical implications highlight the importance of considering bariatric surgery in patients with ocular hypertension.