Abstract
assisted reproduction technology (ART) is up-trending, therefore number of babies born by ART is increasing. ART may influence the secondary sex ratio (SSR) compared to natural conception. to evaluate the effect of ART on SSR. a pilot retrospective medical records review study was conducted on 201 live-birth babies born to couples attended Albayda Fertility Centre. 97 babies were born by ART procedures [intrauterine insemination (IUI) and intracytoplasmic sperm injection (ICSI)] and the remaining were born by non-ART (medical treatment or post-hysteroscopy). The overall SSR was 46%, SSR for non-ART babies was (54.8%) higher than that for the ART offspring (47.4%), however, the difference was non-significant. More girls were born as a result of ICSI (SSR= 43.7%). In contrast, more males were born following IUI (SSR=47.7%) but the difference was insignificant. Regarding the stage of embryo transfer (ET) in babies born by ICSI, a higher but a non-significant difference (Fisher’s Exact test = 0.9) was found in blastocyst stage than the cleavage stage. ART might cause a bias in sex ratio at birth and this change in SSR was found to be affected by the ART procedure applied. The mechanism of these effects is still controversial, larger and multi-centric studies are still warranted.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
