Abstract
Chronic kidney disease (CKD) is a disease characterized by the gradual and functional loss of renal mass, affecting its physiology leading to clinical manifestations. The CKD reaches dogs of several breeds causing important clinical alterations. Some laboratory tests are determinant for the correct diagnosis and thus for the implementation of the most appropriate treatment. The urinalysis, urinary protein-creatinine ratio (UPC) evaluation, urea, and creatinine dosage together with the symmetric dimethylarginine dosage (SDMA), urinary tract ultrasonography and blood pressure monitoring, are the main methods used for diagnosis. In this way, this work aimed to report a case of CKD in a Teckel dog attended at the Veterinary Hospital of the Federal University of Jataí (UFJ), discussing the main clinical manifestations, laboratory, and image alterations, as well as the correct staging according to IRIS (Interest Renal International Society), from which the best treatment option to be adopted is determined.
Highlights
Chronic kidney disease (CKD) is a progressive disease characterized by irreversible lesions in the renal parenchyma, resulting from the evolution of the primary disease, causing a decrease in the functional renal mass leading the kidneys to a loss in the performance of their functions, mainly related to the control of extracellular fluids (Hall et al, 2016; Galvão; Carvalho, 2017)
The objective of this work was to report a case of CKD in a Teckel dog attended at the Veterinary Hospital of the Federal University of Jataí (UFJ), presenting the main clinical manifestations, laboratory and imaging changes that led to the staging as recommended by International Renal Interest Society (IRIS) (Interest Renal International Society)
Chronic kidney disease in its initial stage has a non-specific clinical manifestation, with changes found in other diseases
Summary
Chronic kidney disease (CKD) is a progressive disease characterized by irreversible lesions in the renal parenchyma, resulting from the evolution of the primary disease, causing a decrease in the functional renal mass leading the kidneys to a loss in the performance of their functions, mainly related to the control of extracellular fluids (Hall et al, 2016; Galvão; Carvalho, 2017). For. Rodriguez (2012), CKD represents the progressive and irreversible loss of functional kidney tissue and often the determining cause of the initial renal injury is not possible, since the components of the nephron act independently. DKC is characterized by a reduction in the glomerular filtration rate (GFR), remaining above 50% for a period longer than three months (Galvão; Carvalho, 2017). According to Thrall et al (2015), GFR is a good indicator of renal function because it is directly related to the number of functional nephrons. Hall et al (2016) stated that GFR below 30% indicates imminent renal failure
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