Abstract
DOEGE-POTTER syndrome is a paraneoplastic syndrome in which hypoglycemia results from tumors producing insulin-like growth factor (IGFII). It is most often the solitary fibrous tumor of the pleura. These are rare and may be discovered incidentally, during non-specific respiratory symptoms or during hypoglycemia. Hypoglycemia occurs in large tumors and disappears after surgery, which is the treatment of choice, allowing permanent cure in the majority of cases.
Highlights
DOEGE-POTTER syndrome is a rare paraneoplastic syndrome, initially described in 1930 by Doege and Potter and mainly involving solitary pleural fibrous tumors
We report the case of a 61-year-old patient followed in Pasteur Hospital for a local recurrent malignant neurofibromatous tumor presenting recurrent hypoglycaemia with hypersecretion of insulin-like growth factor
We report the case of a 61-year-old patient followed for solitary fibrous tumor of the pleura who underwent video-thoracoscopic resection in 2009, remained under surveillance
Summary
DOEGE-POTTER syndrome is a rare paraneoplastic syndrome, initially described in 1930 by Doege and Potter and mainly involving solitary pleural fibrous tumors. We report the case of a 61-year-old patient followed in Pasteur Hospital for a local recurrent malignant neurofibromatous tumor presenting recurrent hypoglycaemia with hypersecretion of insulin-like growth factor. Hypoglycemia is an infrequent complication of these tumors, via an insulin-like growth factor secretion mechanism, and may be indicative of it. These tumors have a low rate of malignancy, around 12% to 15%.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: American Journal of Biomedical Science & Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
