Abstract

Objective: World-wide series show some differences in the incidence and clinicopathologic features of salivary gland tumors. Methods: A total of 248 cases of SGTs diagnosed in our hospital between 1998 and2013 were reviewed with respect to their clinicopathologic features. Results: There were 128 male and 116 female patients with a mean age of 49.2. Of these 248 tumors 214 were benign and 34 were malignant. The mean age of the patients with benign tumors was 48.6 years and with malignancies was 55.3 years. The most common site was the parotid gland (83.5%) followed by submandibular and minor ones. Pleomorphic adenoma (50.4%) was the most common benign tumor and affected female patients more frequently. It is followed by Warthin’s tumor that favored parotid gland. Adenoid cystic carcinoma was the most frequent malignant tumor followed by mucoepidemid carcinoma and carcinoma ex pleomorphic adenoma and the majorities were located in the submandibular gland. Conclusion: In the present study, epidemiological data was compared with other worldwide series. Our retrospective study revealed that; benign tumors were more frequent, major salivary glands were more affected by both benign and malignant tumors than minor salivary glands and the parotid gland was the most affected site. Epidemiological data in the various parts of the world can be helpful for a better understanding of SGT's biology and characteristics. Key words: Salivary gland, benign, malignant, tumors, epidemiology

Highlights

  • Salivary gland tumors (SGTs) consist of a group of heterogeneous lesions with complex clinicopathologic characteristics and distinct biological behavior that correspond to approximately 3% to 10% of the neoplasms of the head and neck region [1,2,3,4,5]

  • Our retrospective study revealed that; benign tumors were more frequent in the salivary glands, major salivary glands were more affected by both benign and malignant tumors than minor salivary glands and the parotid gland was the most affected site

  • Adenoid cystic carcinoma was the most frequent malignant tumor followed by mucoepidemid carcinoma and carcinoma ex pleomorphic adenoma

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Summary

Introduction

Salivary gland tumors (SGTs) consist of a group of heterogeneous lesions with complex clinicopathologic characteristics and distinct biological behavior that correspond to approximately 3% to 10% of the neoplasms of the head and neck region [1,2,3,4,5]. Epidemiological studies have shown geographical differences in the incidence and frequency of histological subtypes of SGTs [1]. In this retrospective study, hospital records of 244 patients with salivary gland tumors were documented with demographic features and histological diagnosis

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