Docetaxal induced scleroderma like disease

Abstract

Scleroderma like skin disease is a rare entity among the drug induced dermatological manifestations. It is attributed to various drugs and recently to certain oncological medications especially taxanes. Despite being an efficacious chemotherapeutic agent, it results in scleroderma like skin lesions rarely it resolves in some patients if detected early with omission of the culprit drug with or without steroids. Despite its rarity in literature untreated cases develop severe functional limitation due to skin fibrosis. After an exploration of literature search herein we report the first case of docetaxal induced scleroderma in a Sri Lankan which was detected and promptly treated with steroids successfully. We report this case to make clinicians aware about this condition when encountered with a patient having skin fibrosis with background history of chemotherapy, the possibility of a drug induced scleroderma.