Do water-extractible high-molecular substances of animal organs belong to parenchyma or connective tissue? (A supplementary note to our cancer studies).

Abstract

From pig stomachs mucosa and submucosa were mechanically separated together and then roughly divided into themselves after swelling the mucosa by the aid of a dilute NaOH. The dilute alkali, which had drawn out the components of the epithelial cells in part, and the watery extracts of the mucosa and of sumbucosa were fractioned to obtain from each 1) a fraction containing a glucidamin or glucidamins precipitahle from water at pH 2.0, 2) that containing glucidamins soluble in glacial acetic acid and 3) the group carbohydrate. The corresponding products from the different sources proved similar in composition and other respects (optical rotation, anti-isoagglutinative force and else). The largest yields of them were given from the mucosa except that, among the fractions precipitable at, pH 2.0, the one that had been extracted by the alkali exceeded markedly the one from the mucosa (The crude material from the alkali did not exactly correspond to those from mucosa and submucosa). The finding probably leads to a general conclusion that the water-extractible high-molecular components of animal organs belong to paren-chymal cells.