Do Susceptibilities to Cervical Cancer and Inflammatory Bowel Disease Have Common Underpinnings

Abstract

Whether vulnerability to cervical cancer and inflammatory bowel disease (IBD) are linked remains unclear. To investigate this issue, researchers evaluated a national cohort in Denmark that included 18,691 women with ulcerative colitis and 8717 with Crohn disease. Women with previously diagnosed ulcerative colitis had modestly increased risk for low-grade and high-grade squamous intraepithelial lesions (incidence rate ratio, 1.15 and 1.12, respectively) but no increase in risk for cervical cancer. Those with previously diagnosed Crohn disease …