Abstract
One hundred and ninety six admissions to a coronary care unit who had intravenous (‘Venflon’) cannulae inserted were studied to see whether the addition of heparin to flushing solutions diminished clotting in cannulae, or reduced associated thrombophlebitis. Comparing 0.9% saline with a standard low dose dilution of heparin (10 units/ml) in a controlled trial, no differences were found in the incidence of inflammation, or of clotting in cannulae. Since heparin is more expensive than saline, may interact with other intravenous drugs, and might affect systemic anti-coagulation, routine use of it in coronary care units for flushing intravenous cannulae is not recommended.
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