Abstract
PICO question
 In dogs with cranial cruciate ligament disease treated non-surgically with rehabilitation, is the outcome inferior/equivalent/superior as measured by owner and/or veterinarian evaluation to dogs treated non-surgically without rehabilitation?
 
 Clinical bottom line
 Category of research question
 Treatment
 The number and type of study designs reviewed
 Four papers were critically appraised. One paper reviewed was a prospective, randomised clinical trial. The remaining three papers were retrospective cohort studies
 Strength of evidence
 Weak
 Outcomes reported
 There are no studies available that directly compare dogs managed non-surgically with and without rehabilitation following cranial cruciate ligament injury. In one study, 66% of dogs treated non-surgically with rehabilitation are reported to have successful outcomes 1 year following initiation of treatment. For dogs managed non-surgically without rehabilitation, successful outcomes varied from 19%–90% of cases among several retrospective studies
 Conclusion
 There is evidence suggesting the addition of rehabilitation to conservative therapy is beneficial, but based on the current literature, it is impossible to say whether it is superior to conservative treatment without rehabilitation
 
 How to apply this evidence in practice
 The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
 Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
 
Highlights
Dogs were randomly assigned: N=20 dogs nonsurgical group – physical therapy, weight loss, and NSAID administration N=20 dogs surgical group – tibial plateau leveling osteotomy, physical therapy, weight loss, and NSAID administration All dogs were administered deracoxib once per day at [1,2] mg/kg for 12 weeks Weight loss program designed to achieve 0.5% to 2%
Dogs received a minimum of six supervised physical therapy sessions
Sessions were individually designed for each dog
Summary
PICO question In dogs with cranial cruciate ligament disease treated non-surgically with rehabilitation, is the outcome inferior/equivalent/superior as measured by owner and/or veterinarian evaluation to dogs treated nonsurgically without rehabilitation?. The remaining three papers were retrospective cohort studies Strength of evidence Weak Outcomes reported There are no studies available that directly compare dogs managed non-surgically with and without rehabilitation following cranial cruciate ligament injury. For dogs managed non-surgically without rehabilitation, successful outcomes varied from 19%–90% of cases among several retrospective studies Conclusion There is evidence suggesting the addition of rehabilitation to conservative therapy is beneficial, but based on the current literature, it is impossible to say whether it is superior to conservative treatment without rehabilitation.
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