Do chronic alcoholics have intact implicit memory? An ERP study

Abstract

In order to investigate whether visual object priming differs from visual word priming and whether the visual repetition priming in chronic alcoholic patients is impaired, we performed an ERP study on 27 male control and 67 male alcoholic subjects. Sixty-one electrodes were employed to record ERPs that were elicited by random presentations of object pictures, words, and scrambles for both pictures and words. We also used an implicit task that required subjects to identify whether each stimulus was recognizable. The current experiment revealed that (1) the reaction times to both recognizable picture and word stimuli were significantly shortened by the prior exposures of the same stimuli, (2) control subjects reflected visual object and word priming in different ERP components with different topographic patterns, (3) alcoholic subjects manifested visual word priming in the same ERP component as controls, and (4) the differences in ERP components, both in amplitude and topographic distribution, between the two groups occurred mainly in the different stimuli. These data suggest that the visual object and word priming have distinctive neural processes. The visual object priming in alcoholic subjects may be impaired while the visual word priming seemed to be intact.