Abstract

Background: This paper reports the performance of ICD-10 diagnosed Bipolar affective disorder (BPAD) patients on a well recognised measure of theory of mind (ToM) that commonly elicits group related differences in schizophrenia research.
 Aims: (1) To assess Theory of mind in patients of Bipolar Affective Disorder. 
 (2) To examine effect of mood on Theory of Mind.
 Method: Three groups were formed namely Control, BPAD (M) and BPAD (D). Each group was socio-demographically suitably matched and had 30 participants. Active symptomatology was assessed by using YMRS and MADRS in BPAD(M) and BPAD(D) cases respectively. Theory of mind was calculated using Landon and Clotheart (1999) Picture Sequencing Task.
 Results: Relative to controls, bipolar patients performed significantly worse on the ToM relevant false belief script in picture sequencing task but not on other types of task stories. No significant difference was observed in the ToM performance between the phase of bipolarity.
 Conclusion: The results support previous evidence of ToM deficit in BPAD and indicate a potential endophenotypic overlap in the phenomenology of both Schizophrenia and BPAD.
 Keywords: Theory of Mind, YMRS, MADRS, Picture Sequence Task

Highlights

  • Background: This paper reports the performance of ICD-10 diagnosed Bipolar affective disorder (BPAD) patients on a well recognised measure of theory of mind (ToM) that commonly elicits group related differences in schizophrenia research

  • Active symptomatology was assessed by using Young Mania Rating Scale (YMRS) and Montgomery Asberg Depression Rating Scale (MADRS) in BPAD(M) and BPAD(D) cases respectively

  • We aimed to examine ToM performance on the picture sequencing task in a well characterised sample of bipolar affective disorder patients to determine whether impairments commonly elicited by it in schizophrenia, extend to bipolar affective disorder as well

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Summary

Introduction

This paper reports the performance of ICD-10 diagnosed Bipolar affective disorder (BPAD) patients on a well recognised measure of theory of mind (ToM) that commonly elicits group related differences in schizophrenia research. Aims: (1) To assess Theory of mind in patients of Bipolar Affective Disorder. Method: Three groups were formed namely Control, BPAD (M) and BPAD (D). Active symptomatology was assessed by using YMRS and MADRS in BPAD(M) and BPAD(D) cases respectively. Theory of mind was calculated using Landon and Clotheart (1999) Picture Sequencing Task. Results: Relative to controls, bipolar patients performed significantly worse on the ToM relevant false belief script in picture sequencing task but not on other types of task stories.

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