Abstract
How well anthropometric indices such as body mass index (BMI), waist circumference, waist-stature ratio, and waist index correlate with direct measures of body composition (lean body mass, body fat) in men and women with chronic heart failure (CHF) has not been reported. Body composition was assessed by dual-energy x-ray absorptiometry in 140 patients with CHF. Age-adjusted Pearson correlations between each index and measures of body composition for men and women were calculated. Diagnostic accuracy of detecting obesity or high central fat was also examined. In men, all of the anthropometric indices except waist index were just as strongly correlated with lean body mass (correlation coefficients varied between 0.56 for waist-stature ratio to 0.74 for BMI) as with percentage of body fat (correlation coefficients varied between 0.72 for BMI to 0.79 for waist circumference). In women, all 4 anthropometric measures were unable to significantly differentiate between body fat and lean body mass. The positive likelihood ratios for the detection of obesity varied between 2.26 for waist circumference and 3.42 for BMI, waist-stature ratio, and waist index. Anthropometric indices do not accurately reflect body composition in patients with CHF, especially in women. When accurate assessment of body composition is required, direct measurements should be obtained.
Highlights
Title Do anthropometric indices accurately reflect directly measured body composition in men and women with chronic heart failure?
Total body fat was assessed by dual energy x-ray absorptiometry (DEXA) performed with a Hologic Series Delphi-A Fan Beam X-ray Bone Densitometer after it was determined that patients did not have fluid overload
How well anthropometric indices such as body mass index (BMI), waist circumference, waist-stature ratio, and waist index correlate with direct measures of body composition in men and women with chronic heart failure (CHF) has not been reported
Summary
Title Do anthropometric indices accurately reflect directly measured body composition in men and women with chronic heart failure?. Do Anthropometric Indices Accurately Reflect Directly Measured Body Composition in Men and Women With Chronic Heart Failure?. Obesity as categorized by body mass index (BMI) is paradoxically associated with better survival rates in patients with chronic heart failure (CHF),[1] a relationship that has been termed the obesity paradox.[2] The validity of the obesity paradox has been questioned, in part because BMI is a surrogate measure of body fat and may not accurately reflect adipose tissue stores. The purpose of this study was to further explore the relationship between various anthropometric indices and body composition by examining the sex-specific diagnostic accuracy of BMI, waist circumference (WC), waist index (WI), and waist-stature ratio (WSR) to detect obesity in patients with CHF
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