Abstract
The complex, [Cu2LCl2]Cl2 · 3H2O, where L = the macrocyclic ligand bis-p-xylylBISDIEN Schiff base, has been prepared and characterized by elemental analysis, i.r. and mass spectra. The binding of the complex with calf thymus DNA has been investigated using absorption spectroscopy, cyclic voltammetry, fluorescence spectroscopy and viscosity measurements. The results suggest that the complex can bind to CT DNA by intercalation via the aromatic ring on the macrocycle into the base pairs of DNA. The complex exhibits efficient nuclease activity.
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