DNA sequence compression using RP/GP2 method with information storage and security

Abstract

In the field of bioinformatics, the storing and transmission of deoxyribonucleic acid (DNA) is essential for compression rate, ratio and encryption point of view. The DNA sequence requires huge space for storing and time for encryption causing considerable delay transmission of information. The most of the users demand low storage and computational cost, therefore efficient algorithm is required for compression. Proposed algorithm will be based on combinations of reverse and palindrome (RP) technique or genetic palindrome and palindrome (GP2) technique substring substitution. The variable substring will be replaced by the corresponding American Standard Code for Information Interchange (ASCII) code which is extracted RP/GP2. The transmission of DNA/RNA/Protein sequence over wireless communication is common issue. The size of DNA sequence is growing twice in a year proportionally. As a result, security of these data from unauthorized user is essential. The proposed selection encryption reduces the computational recourses for this data. The DNA sequence security is ensured by signature which depends on ASCII code and dynamic library file acting as a key. This approach shows that 95% of original file is modified when 44–45% is encrypted. The experimental results shows that the compression rate is 3.7750 bits/base.