Abstract
DNA is present in most of the cells in our body, which is unique in each and every individual, and we leave a trail of it everywhere we go. This has become an advantage for forensic investigators who use DNA to draw conclusion in identification of victim and accused in crime scenes. This review described the use of genetic markers in forensic investigation and their limitations.
Highlights
Forensic identification is a universal method used to establish the veracity in the process of forensic investigation
1983: A critical development in the history of forensic genetics came with the advent of polymerase chain reaction (PCR) process that can amplify specific regions of deoxyribonucleic acid (DNA), which was conceptualized by Kary Mullis, a chemist; later he was awarded Nobel Prize in 1993.7
1984: Alec Jeffrey introduced DNA fingerprinting in the field of forensic genetics, and proved that some regions in the DNA have repetitive sequences, which vary among individuals
Summary
Forensic identification is a universal method used to establish the veracity in the process of forensic investigation. 1980: First polymorphic locus was reported.6 1983: A critical development in the history of forensic genetics came with the advent of PCR process that can amplify specific regions of DNA, which was conceptualized by Kary Mullis, a chemist; later he was awarded Nobel Prize in 1993.7 1984: Alec Jeffrey introduced DNA fingerprinting in the field of forensic genetics, and proved that some regions in the DNA have repetitive sequences, which vary among individuals. Due to this discovery, first forensic case was solved using DNA analysis.[8]. Classification of Human Genome[2] Based on the structure and function, Classification of Human Genome into following different types (►Fig. 2)
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