Abstract
The specific activity of DNA polymerase of Tetrahymena can be increased by treatment of the cells with methotrexate plus uridine. The increase does not occur in the presence of protein synthesis inhibitors and is also affected by an inhibitor of RNA synthesis. The specific activity of DNA polymerase can also be increased by treatment of Tetrahymena with ultraviolet irradiation. It is suggested that the increase in enzymic specific activity represents de novo synthesis of DNA polymerase in response to agents which cause repairable damage to Tetrahymena DNA.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
