Abstract

DNA Ploidy and Chromosome (FISH) Pattern Analysis of Peripheral Nerve Sheath Tumors

Highlights

  • “smart” oligonucleotide Fluorescence in situ Hybridization (FISH) using pools of designed, synthesized and fluorescence labelled, single stranded oligonucleotides, or a combination of such oligonucleotides with nanoprobe approaches [1]

  • The FISH analysis used DNA probes specific for centromeric regions combined with automatic image analysis

  • The data support the notion that the ploidy pattern determination combined with FISH analysis is a highly useful diagnostic tool

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Summary

Introduction

“smart” oligonucleotide FISH using pools of designed, synthesized and fluorescence labelled, single stranded oligonucleotides, or a combination of such oligonucleotides with nanoprobe approaches [1]. DNA ploidy and chromosome (FISH) pattern analysis of peripheral nerve sheath tumors To the Editor, This report contains highly informative image DNA cytometry and Fluorescence in situ Hybridization (FISH) data on the DNA ploidy analysis of peripheral nerve sheath tumors [3].

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