Abstract

In article number 2000102, Ilia Platzman, Kerstin Göpfrich, Joachim P. Spatz, and co-workers engineer minimal contractile actomyosin networks for synthetic cells. They employ DNA nanotechnology combined with light-triggered actuation to control the contraction dynamics. Symmetry breaking is achieved and quantified in cell-sized compartments, showcasing how an engineering approach to synthetic biology can provide a shortcut toward complex function.

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