Abstract
The rapid development of DNA nanotechnology has enabled the precise bottom-up integration of metal nanoparticles (NPs) on a nanometer scale. The recent introduction of the DNA origami technique has facilitated even more complicated control of the positioning of not only 2 dimensional (D) but also 3D structures. The basic idea and recent distinctive examples of such metal NP arrays on DNA nanostructure are briefly reviewed. DNA nanotechnology has enabled precise bottom-up integration of metal nanoparticles (NPs) on a nanometer scale. The DNA origami technique facilitated still more complicated control of the positioning not only in 2 dimensional (D) but also in 3D structures. We constructed an alternating streptavidin/gold NP heteroarray with 26 nm separation using a nanometer-sized cavity (a DNA well) embedded in a 2-nm-thick DNA origami sheet. The basic idea and other recent examples of such metal NP arrays on DNA nanostructures are reviewed.
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