Abstract
基因组DNA甲基化是目前发现的最主要的一种表观遗传修饰形式，高甲基化（hypermethylation）的DNA染色质构象发生改变，导致抑癌基因转录失活，在肿瘤发生发展中具有重要意义。近年来，DNA甲基化在肺癌，主要是非小细胞肺癌（non-small cell lung cancer, NSCLC）的研究中取得较大进展，为NSCLC早期诊断、风险评估、预后判断和干预治疗提供了新的靶点。
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
