Abstract
Nanotechnology Synthetic DNA can be used to build nanomachines that can generate, transmit, and sense mechanical forces. In a Perspective, Blanchard and Salaita discuss recent developments in DNA devices and their applications, particularly to force generation in biological interactions, such as ligand-receptor binding. These advances have provided insight into the mechanics of the biological world and have improved our understanding of cellular interactions. Science , this issue p. [1080][1] [1]: /lookup/doi/10.1126/science.aax3343
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