DNA Damage-Inducible Gene Expression and Formation of 5-Fluorouracil-Resistant Mutants in Escherichia coli Exposed to 2-Dodecylcyclobutanone

Abstract

-galactosidase reporter constructs, and for the ability to increase the formation of 5-fluorou-galactosidase reporter constructs, and for the ability to increase the formation of 5-fluorou-galactosidase reporter constructs, and for the ability to increase the formation of 5-fluorou-galactosidase reporter constructs, and for the ability to increase the formation of 5-fluorour r r r racil (5-FU)–r acil (5-FU)–r acil (5-FU)–r acil (5-FU)–r acil (5-FU)–resistant mutants esistant mutants esistant mutants esistant mutants esistant mutants. . . . When When When When When E. coli was exposed to 125, 250, 500, and 1000 was exposed to 125, 250, 500, and 1000 was exposed to 125, 250, 500, and 1000 was exposed to 125, 250, 500, and 1000 was exposed to 125, 250, 500, and 1000 g/mL 2-DCB g/mL 2-DCB g/mL 2-DCB g/mL 2-DCB g/mL 2-DCB, with and , with and , with and , with and , with and without ex without ex without ex without ex without exogenous metabolic activ ogenous metabolic activ ogenous metabolic activ ogenous metabolic activ ogenous metabolic activation, no incr ation, no incr ation, no incr ation, no incr ation, no increase in ease in ease in ease in ease in dinD, nfo, recA, or