Abstract
Objective: Better strategies are needed to stratify patients with epithelial ovarian cancer (EOC) to select treatment regimens most likely to be effective. Here we present a robust strategy to holistically assess broad spectrum DNA damage and repair (DDR) defects in EOC termed repair assisted damage detection (RADD). RADD measures the DNA damage left behind by defective repair machinery to characterize DNA repair defects to predict treatment response for EOC.
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