DMD – THERAPY: P.294 Does steroid therapy influence pulmonary function decline in adults with Duchenne muscular dystrophy after loss of ambulation?

Abstract

Data from longitudinal paediatric Duchenne Muscular Dystrophy (DMD) cohorts has shown significant benefits of corticosteroids (CS) in patient treatment and management. Additionally, current scientific literature suggests that CS therapy delays the onset of pulmonary decline by approximately two years. However, there is limited data on the effects of CS in patients after loss of ambulation. Despite the updated in 2018 standards of care for DMD, there is still inconsistency in clinical care for non-ambulant patients across the UK.