Abstract

Background: Breast cancer is one of the high prevalence cancers worldwide affecting women based on various factors. Hormonal changes are amongst the factors involved in the development of breast cancer. The basic hormones involved include estrogen and progesterone with human epidermal receptor-2 (HER2) which could be either over expressed or not at all expressed. Therefore, studies were conducted on the DMBA induced breast cancer model. Keywords: Breast cancer, DMBA, Estrogen, Progesterone, HER-2, DNA, carcinomace.

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