Abstract
Diabetes mellitus (DM) is an important disease that negatively affects fetal development and women with pregestational diabetes have an increased risk for adverse pregnancy outcomes, including a markedly increased risk for birth defects. In this report, a newborn with absent radius associated with pregestational diabetes was presented. A male newborn was born at 40th gestational week from a 20-year-old mother by cesarean section. The patient had shortness in the limbs, hypoplastic right thumb and flexion contracture at his right hand besides respiratory distress.To our knowledge, with this case report, we would like to share the second case of diabetic mother’s infant with absent radius in the literature.
Highlights
Diabetes mellitus (DM) is an important disease that negatively affects fetal development during pregnancy and causes important metabolic disorders in newborns.[1]
Many factors have been accused for increasing congenital anomalies in infants of diabetic mothers including genetic causes, teratogenic agents, maternal vascular disease and metabolic effects of maternal diabetes
Hyperinsulinemia and hyperglycemia developing on the basis of beta cell damage and fetal insulin resistance are the main effective pathogenic factors.[8]
Summary
Diabetes mellitus (DM) is an important disease that negatively affects fetal development during pregnancy and causes important metabolic disorders in newborns.[1]. Diabetes mellitus (DM) is an important disease that negatively affects fetal development during pregnancy and causes important metabolic disorders in newborns.[1] Gestational diabetes occurs in 4-7% of pregnancies.[2] Among gestational diabetes, the incidence of infants born to diabetic mothers with gestational DM is 93% and mothers with insulin dependent pregestational DM is 7%.3 Babies of pregestational diabetic mothers have an increased risk of congenital malformations.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
