Abstract
Erythrocyte division occurs in the blood of goldfish, Carassius auratus L., and is particularly prominent during response to respiratory stresses. The process involves nuclear elongation followed by cellular elongation, central constriction, and attenuation culminating in cell separation. Cytomorphic criteria developed in an earlier study of red cell maturation in this species suggest that the process is restricted to juvenile cells: those possessing the organelles required for hemoglobin synthesis. Consistent with this, but in distinct contrast to mature erythrocytes, dividing cells resemble juvenile cells in their incorporation of 55Fe. This is subsequently detectable by autoradiography in hemoglobin electropherograms. Immuno-fluorescent antibody probes for tubulin and actin revealed an ordered sequence of cytoskeletal changes during the division process. However, the nuclei of dividing cells do not take up [3H]thymidine, and although colchicine and nocodazole treatment led to the appearance of metaphase figures in pronephric and splenic erythroid cells, these were not evident in dividing cells. The nature and possible significance of the process are discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
