Diversity-Based Approaches to Selective Biomimetic Oxidation Catalysis

Abstract

Publisher Summary This chapter discusses diversity-based approaches to selective biomimetic oxidation catalysis. The chapter describes the achievements and challenges in diversity-based biomimetic oxidation, with respect to both the discovery of novel and the optimization of existing catalyst systems. The development of methods for the selective and atom-economic oxidation/ oxygenation of organic substrates belong to the most challenging fields of contemporary chemical research, both in the academic and the industrial environment. The identification of an active and selective catalyst for a given transformation is a multi-dimensional problem, involving inter alia optimization of the ligand structure, the nature of the metal ion, etc. The classical approach to catalyst discovery and optimization involves one-by-one synthesis and evaluation of catalyst candidates. The identification of an active and selective catalyst for a given transformation is a multi-dimensional problem, involving inter alia optimization of the ligand structure, the nature of the metal ion, etc.