Abstract
In a study of the space distribution of eight red blood cells markers in European and Asian populations, evidence for a longitudinal cline of GLO, ESD, PGP, AK, and 6-PGD allele frequencies was found. The respective Fst values appeared significantly greater than those computed at loci whose allele frequencies are not associated with longitude, namely ADA, GPT, and SOD. A systematic pressure appears to have acted upon the former systems, even though the effects of selection can partially overlap with the effects of migratory movements, which have already been demonstrated in the studied area. Conversely, random genetic drift, or random fluctuation of selection coefficients, cannot account for the observed gene frequency diversity.
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