Abstract
About 10 percent of women (6.1 million) in the United States ages 15-44 have difficulty getting pregnant or staying pregnant. Addressing fertility challenges requires an understanding of not only the causes of infertility, but also modifiable risk factors that can impact the likelihood of pregnancy. However, current research on factors influencing conception is often conducted among people who are already engaged in medical fertility treatments. In addition, existing databases are not representative of the U.S. population demographically. This retrospective study describes the demographics of participants of a digital fertility platform who were seeking fertility guidance prior to conception. Demographic data collected from participants who enrolled in Doveras Fertility Inc. (Doveras)’s digital health offerings in 2023 and 2024 were analyzed. Doveras offers personalized preconception lifestyle and behavioral intervention programs, delivered through an innovative digital fertility health platform, for individuals and couples to improve various endpoints along the reproductive and maternal health journey. This paper reports on the inception cohort of the first 600 enrolled participants (Doveras Preconception Cohort I), a subset of a wider pool of Doveras participants enrolled. Doveras achieved this enrollment of a notably diverse and representative population: 65.9% of female-identifying participants identify as White and 34.1% as non-white; 60.5% of male-identifying participants identify as White and 39.5% identify as non-white. The cohort also demonstrates a wide geographical spread, with participants recruited from 46 U.S. states, and represents a population that may have limited access to preconception healthcare: more than half (61%) of participants live in states with 13 OBGYNS or fewer per 100,000 population. The Doveras digital fertility platform presented herein may provide an opportunity to reach a broader and more diverse U.S. population during the preconception period than currently has access to medical fertility care.
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