Abstract
Venous blood was sampled in 3-h intervals from 5 men and 4 women under conditions of normal daily activity during 24 h (Series I). Hematocrit, hemoglobin concentration in blood and red cells, sodium, potassium, magnesium and chloride concentrations in plasma and red cells, protein, calcium and inorganic phosphate concentrations and standard bicarbonate in plasma, pH in blood and red cells, pCO2 in blood were measured or calculated. Most concentration curves showed biphasic patterns with night minima which were significant for hemoglobin, hematocrit and pH in blood, protein, sodium, calcium and standard bicarbonate in plasma, potassium and pH in red cells. Inorganic phosphate in plasma alone exhibited a definite day minimum. A second series (6 subjects) with measurements made only between 06.00 and 12.00 showed changes similar to those in Series I with an additional small increase of red cell sodium concentration at noon. In a third series, where 6 subjects remained in a recumbent position up to midday, the morning increase of [Hb], Hct, pH and standard bicarbonate was clearly reproducible.
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