Diuretic use and the risk of breast cancer

Abstract

Some antihypertensive medications, particularly calcium channel blockers, have been associated with breast cancer risk, although the evidence is inconsistent. 1 Diuretics comprise the antihypertensive drug class with the longest record of use 2 and are one of the most commonly used drug classes in the United States, 3 yet have received less study than other antihypertensive classes. We have assessed the relation of diuretic use to the risk of invasive breast cancer using 30 years of data from our ongoing hospital-based case-control surveillance study.