Abstract

Hypertension a major risk factor for cardiovascular disease and is the most widely recognized modifiable risk factor for this disease. There is little information on the prevalence and risk factors for hypertension in Zambia, and in particular in rural areas of the country. In order to contribute to the existing global literature on hypertension, particularly in rural Zambia, this study was conducted to determine the prevalence of hypertension and its correlates in two rural districts of Zambia, namely Kaoma and Kasama. A cross-sectional study using a modified World Health Organization (WHO) global non communicable diseases (NCD) surveillance initiative NCD-STEPwise approach was used. Proportions were compared using the Yates' corrected χ2 test, and a result yielding a p-value of less than 5% was considered significant. Bivariate and multivariate logistic regression analyses were conducted. Factors that were significantly associated with the outcome in bivariate analyses were considered in a multivariate logistic regression analysis using a backward variable selection method. Adjusted odds ratios (AOR) and their 95% confidence intervals (CI) were reported. In total, 895 participants from Kaoma and 1198 participants from Kasama took part in the surveys. Overall, 25.8% participants (27.5% male, 24.6% female; p=0.373) in Kaoma and 30.3% (31.3% male, 29.5% female; p=0.531) in Kasama were hypertensive. In Kaoma, age and BMI were independently associated with hypertension. Compared with participants aged 45 years or older, participants aged 25-34 years were 60% (AOR=0.40, 95% CI [0.21, 0.56]) less likely to be hypertensive. Participants with BMI <18.5 and 18.5-24.9 were 54% (AOR=0.46, 95% CI [0.30, 0.69]) and 31% (AOR=0.69, 95% CI [0.49, 0.98]) less likely to be hypertensive compared with participants with BMI ≥30. In Kasama, age, smoking and heart rate were significantly associated with hypertension in multivariate analysis. Participants 25-34 years were 49% (AOR=0.51, 95% CI [0.41, 0.65]) less likely to be hypertensive compared with participants 45 years or older. Compared with participants who were non-smokers, smokers were 21% (AOR=1.21, 95% CI [1.02, 1.45]) more likely to be hypertensive. Participants who had heart rate >90 beats/min were 59% (AOR=1.59, 95% CI [1.17, 2.16]) more likely to be hypertensive compared with participants who had heart rate 60-90 beats/min. The findings reveal that hypertension is prevalent among rural residents in Kaoma and Kasama, Zambia. The disease is highly associated with age, BMI, smoking and heart rate. Efficient preventive strategies are needed to halt the growing trend of non-communicable diseases through the control of risk factors highlighted in this study.

Highlights

  • IntroductionHypertension is a public health challenge worldwide with an increasing trend in developing countries

  • Hypertension a major risk factor for cardiovascular disease and is the most widely recognized modifiable risk factor for this disease

  • In developing countries such as Zambia, hypertension adds to the double burden of communicable and non communicable diseases (NCD) in a resourcelow environment characterised by an ineffective health system

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Summary

Introduction

Hypertension is a public health challenge worldwide with an increasing trend in developing countries. Control of hypertension is an effective means for reducing premature cardiovascular disease mortality[4]. In developing countries such as Zambia, hypertension adds to the double burden of communicable and NCD in a resourcelow environment characterised by an ineffective health system. Hypertension has been reported as prevalent in urban populations in Zambia at 34.8% in Lusaka, with major risk factors including age, alcohol use and stress[6]; and in Kitwe at 31.1% with risk factors age and BMI7. As in many other developing countries, hypertension has not been considered a public health problem in Zambia. Public health research in Zambia, rural Zambia, has not considered hypertension or its differential risk factors and patterns of the disease. This study was conducted to determine the prevalence of hypertension and its correlates in the two rural districts of Zambia, namely Kaoma and Kasama

Methods
Study design and participants
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